Microwave enhanced solution synthesis of 1,4-benzodiazepin-5-ones

被引：45

作者：

Santagada, V ^{[1
]}

Perissutti, E ^{[1
]}

Fiorino, F ^{[1
]}

Vivenzio, B ^{[1
]}

Caliendo, C ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Farmaceut & Tossicol, I-80131 Naples, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 12期

关键词：

2-methyl-1,4-benzodiazepin-5-ones; microwave irradiation in solution; medium ring heterocycles;

D O I：

10.1016/S0040-4039(01)00155-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some 2-methyl-1,4-benzodiazepin-5-ones have been synthesized by the application of microwave irradiation. Conventional heating and microwave irradiation of the reactions were compared. Synthesis by microwave irradiation gave the desired compounds in better yields than those obtained by conventional heating. The overall times for the syntheses were considerably reduced. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2397 / 2400

页数：4

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