Predictor index of mortality in dementia patients upon entry into long-term care

被引:17
作者
Carlson, MC
Brandt, J
Steele, C
Baker, A
Stern, Y
Lyketsos, CG
机构
[1] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Ctr Aging & Hlth, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Mental Hyg, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Dept Psychiat & Behav Sci, Sch Med, Neuropsychiat & Memory Grp, Baltimore, MD USA
[4] Copper Ridge Inst, Sykesville, MD USA
[5] Columbia Univ, Coll Phys & Surg, Gertrude Sergievsky Ctr, New York, NY USA
来源
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2001年 / 56卷 / 09期
关键词
D O I
10.1093/gerona/56.9.M567
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background. The purpose of this study was to develop an algorithm that predicts survival in patients with dementia upon entry into long-term care. There are, as yet, no predictive equations developed for those in the late stages of Alzheimer's disease (AD). Methods. This was a prospective, observational study of 132 patients with dementia (61% with AD) followed for up to 5.0 years (median of 41.0 months) after admission to a long-term care facility for dementia patients. Information on demographic characteristics, physical health, and cognitive, emotional, and behavioral characteristics was collected shortly after admission and entered as predictors of time until death in Cox regressions. Findings were used to derive an index predicting mortality. Results. There were 60 deaths among the 132 patients (45.4% mortality), with an average survival of 22.4 months in those who died. Better physical health and the presence of delusions were associated with longer survival. These two variables were aggregated into the Copper Ridge Index (CRI), Each one-point increase on the CRI was associated with a four-fold greater likelihood of death over 5 years. Conclusions. A predictive equation incorporating measures of general physical health and delusions accurately predicted time to death in dementia patients in long-term care.
引用
收藏
页码:M567 / M570
页数:4
相关论文
共 33 条
[1]   THE TEST FOR SEVERE IMPAIRMENT - AN INSTRUMENT FOR THE ASSESSMENT OF PATIENTS WITH SEVERE COGNITIVE DYSFUNCTION [J].
ALBERT, M ;
COHEN, C .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1992, 40 (05) :449-453
[2]   USE OF THE CORNELL SCALE IN NONDEMENTED PATIENTS [J].
ALEXOPOULOS, GS ;
ABRAMS, RC ;
YOUNG, RC ;
SHAMOIAN, CA .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1988, 36 (03) :230-236
[3]   FACTORS ASSOCIATED WITH DURATION OF SURVIVAL IN ALZHEIMERS-DISEASE [J].
BARCLAY, LL ;
ZEMCOV, A ;
BLASS, JP ;
MCDOWELL, FH .
BIOLOGICAL PSYCHIATRY, 1985, 20 (01) :86-93
[4]   MORTALITY OF DEMENTED PATIENTS IN A GERIATRIC INSTITUTION [J].
BELLONISONZOGNI, A ;
TISSOT, A ;
TETTAMANTI, M ;
FRATTURA, L ;
SPAGNOLI, A .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 1989, 9 (02) :193-197
[5]  
BINETTI G, 1993, ACTA NEUROL SCAND, V88, P5
[6]   TIME UNTIL INSTITUTIONALIZATION AND DEATH IN PATIENTS WITH DEMENTIA - ROLE OF CAREGIVER TRAINING AND RISK-FACTORS [J].
BRODATY, H ;
MCGILCHRIST, C ;
HARRIS, L ;
PETERS, KE .
ARCHIVES OF NEUROLOGY, 1993, 50 (06) :643-650
[7]   Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset [J].
Brookmeyer, R ;
Gray, S ;
Kawas, C .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1998, 88 (09) :1337-1342
[8]  
*BUR CENS, 1996, 65 PLUS US
[9]   FACTORS AFFECTING SURVIVAL IN ALZHEIMERS-DISEASE [J].
BURNS, A ;
LEWIS, G ;
JACOBY, R ;
LEVY, R .
PSYCHOLOGICAL MEDICINE, 1991, 21 (02) :363-370
[10]  
DIMASCIO A, 1976, ARCH GEN PSYCHIAT, V33, P599