Design for Manufacture of a Micro-Interdigitated Electrode for Impedance Measurement in a Biochemical Assay

被引:1
作者
Donoghue, Linda [1 ]
Anthony, Brian W. [2 ]
机构
[1] MIT, MEng Mfg Program, Cambridge, MA 02139 USA
[2] MIT, Lab Mfg & Prod, Cambridge, MA 02139 USA
来源
MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS X | 2012年 / 8251卷
关键词
microfluidics; manufacturing; design for manufacture; electrodes; polymer;
D O I
10.1117/12.910492
中图分类号
R318 [生物医学工程];
学科分类号
100103 [病原生物学];
摘要
The performance of interdigitated electrodes for impedance measurements in a microfluidic assay chamber is dependent upon the geometric design of the electrode pattern and can be significantly impacted by variability or defects in manufacturing or materials. For processes which rely on precise electrode performance, it is necessary to minimize variation through robust design and quality control. An interdigitated electrode design was investigated to identify design strategies which maximize electrode sensitivity and minimize performance variability in produced parts, while potentially reducing the complexity of quality testing. Several configurations were developed to address these goals by increasing the sensing region for a specified electrode area and creating designs which can be easily manufactured with low variability. Design modifications included alterations to interdigitated finger orientation, finger geometry, and gap width. Test findings indicate that optimal designs contain narrow gap widths with electrode fingers parallel to the longest dimension of the electrode. These benefits may be further enhanced by replacing straight finger edges with geometrical features, such as scalloped edges. The design changes identified can be used to improve interdigitated electrode performance for an array of applications and to reduce performance variability caused by variation in the manufacturing process.
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页数:6
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