IMMUNOTHERAPY Cancer vaccine triggers antiviral-type defences

被引:16
作者
de Vries, Jolanda [1 ]
Figdor, Carl [1 ]
机构
[1] Radboud Univ Nijmegen, Radboud Inst Mol Life Sci, Med Ctr, Dept Tumor Immunol, NL-6525 GA Nijmegen, Netherlands
关键词
HUMAN DENDRITIC CELLS; IN-VIVO; ANTIGEN; RESPONSES; DEC-205;
D O I
10.1038/nature18443
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
[No abstract available]
引用
收藏
页码:329 / 331
页数:3
相关论文
共 10 条
[1]
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance [J].
Bonifaz, L ;
Bonnyay, D ;
Mahnke, K ;
Rivera, M ;
Nussenzweig, MC ;
Steinman, RM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (12) :1627-1638
[2]
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination [J].
Bonifaz, LC ;
Bonnyay, DP ;
Charalambous, A ;
Darguste, DI ;
Fujii, SI ;
Soares, H ;
Brimnes, MK ;
Moltedo, B ;
Moran, TM ;
Steinman, RM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (06) :815-824
[3]
Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro [J].
Cruz, Luis J. ;
Tacken, Paul J. ;
Fokkink, Remco ;
Joosten, Ben ;
Stuart, Martien Cohen ;
Albericio, Fernando ;
Torensma, Ruurd ;
Figdor, Carl G. .
JOURNAL OF CONTROLLED RELEASE, 2010, 144 (02) :118-126
[4]
T cell exclusion, immune privilege, and the tumor microenvironment [J].
Joyce, Johanna A. ;
Fearon, Douglas T. .
SCIENCE, 2015, 348 (6230) :74-80
[5]
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy [J].
Kranz, Lena M. ;
Diken, Mustafa ;
Haas, Heinrich ;
Kreiter, Sebastian ;
Loquai, Carmen ;
Reuter, Kerstin C. ;
Meng, Martin ;
Fritz, Daniel ;
Vascotto, Fulvia ;
Hefesha, Hossam ;
Grunwitz, Christian ;
Vormehr, Mathias ;
Huesemann, Yves ;
Selmi, Abderraouf ;
Kuhn, Andreas N. ;
Buck, Janina ;
Derhovanessian, Evelyna ;
Rae, Richard ;
Attig, Sebastian ;
Diekmann, Jan ;
Jabulowsky, Robert A. ;
Heesch, Sandra ;
Hassel, Jessica ;
Langguth, Peter ;
Grabbe, Stephan ;
Huber, Christoph ;
Tuereci, Oezlem ;
Sahin, Ugur .
NATURE, 2016, 534 (7607) :396-+
[6]
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo [J].
Kuhn, A. N. ;
Diken, M. ;
Kreiter, S. ;
Selmi, A. ;
Kowalska, J. ;
Jemielity, J. ;
Darzynkiewicz, E. ;
Huber, C. ;
Tureci, O. ;
Sahin, U. .
GENE THERAPY, 2010, 17 (08) :961-971
[7]
Cancer immunotherapy via dendritic cells [J].
Palucka, Karolina ;
Banchereau, Jacques .
NATURE REVIEWS CANCER, 2012, 12 (04) :265-277
[8]
Dendritic-cell immunotherapy:: from ex vivo loading to in vivo targeting [J].
Tacken, Paul J. ;
de Vries, I. Jolanda M. ;
Torensma, Ruurd ;
Figdor, Carl G. .
NATURE REVIEWS IMMUNOLOGY, 2007, 7 (10) :790-802
[9]
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody [J].
Tacken, PJ ;
de Vries, IJM ;
Gijzen, K ;
Joosten, B ;
Wu, DY ;
Rother, RP ;
Faas, SJ ;
Punt, CJA ;
Torensma, R ;
Adema, GJ ;
Figdor, CG .
BLOOD, 2005, 106 (04) :1278-1285
[10]
Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients [J].
Tel, Jurjen ;
Aarntzen, Erik H. J. G. ;
Baba, Tetsuro ;
Schreibelt, Gerty ;
Schulte, Barbara M. ;
Benitez-Ribas, Daniel ;
Boerman, Otto C. ;
Croockewit, Sandra ;
Oyen, Wim J. G. ;
van Rossum, Michelle ;
Winkels, Gregor ;
Coulie, Pierre G. ;
Punt, Cornelis J. A. ;
Figdor, Carl G. ;
de Vries, I. Jolanda M. .
CANCER RESEARCH, 2013, 73 (03) :1063-1075