Positive predictive value of gen-probe APTIMA Combo 2 testing for Neisseria gonorrhoeae in a population of women with low prevalence of N-gonorrhoeae infection

被引：34

作者：

Golden, MR

Hughes, JP

Cles, LE

Crouse, K

Gudgel, K

Hu, JX

Swenson, PD

Stamm, WE

Handsfield, HH

机构：

[1] Univ Washington, Harborview Med Ctr, Div Infect Dis, Seattle, WA 98104 USA

[2] Univ Washington, Dept Biostat, Seattle, WA 98104 USA

[3] Publ Hlth Seattle & King Cty, Spokane, WA USA

[4] Spokane Reg Hlth Dist Lab, Spokane, WA USA

[5] Washington State Dept Hlth, Olympia, WA USA

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 09期

关键词：

D O I：

10.1086/424880

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We collected specimens from women who tested positive for Neisseria gonorrhoeae using the Gen-Probe APTIMA Combo 2 (AC2), and we performed confirmatory tests using a nucleic acid amplification test (NAAT) that targets alternate gonococcal nucleic acid sequences. Among 59,664 specimens, 280 (0.47%) had positive results using AC2; 265 of these specimens were tested using the confirmatory NAAT, of which 258 yielded positive results (positive predictive value, 97.4%; 95% confidence interval, 95.1%-98.8%). Routine confirmatory testing of specimens with positive AC2 gonorrhea test results is not indicated.

引用

页码：1387 / 1390

页数：4

共 9 条

[1] Evaluation of laboratory testing methods for Chlamydia trachomatis infection in the era of nucleic acid amplification [J].