Morphological analysis of mouse lungs after treatment with magnetite-based magnetic fluid stabilized with DMSA

被引：47

作者：

Garcia, MP

Parca, RM

Chaves, SB

Silva, LP

Santos, AD

Lacava, ZGM

Morais, PC

Azevedo, RB ^{[1
]}

机构：

[1] Univ Brasilia, Inst Biol, Dept Genet & Morfol, BR-70910900 Brasilia, DF, Brazil

[2] Univ Brasilia, Inst Fis, BR-70919970 Brasilia, DF, Brazil

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

nanoparticles; magnetic fluid; dimercaptosuccinic acid (DMSA); morphological analysis; lung inflammation; toxicity; mice; biocompatibility;

D O I：

10.1016/j.jmmm.2005.02.053

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Mouse lungs injected with magnetic fluids based on magnetite nanoparticles stabilized by 2,3-dimercaptosuccinic acid were studied. We observed clusters of magnetic nanoparticles inside blood vessels, within the organ parenchyma and cells, as well as increased numbers of leukocytes in the organ. Both the particle concentration and organ inflammation diminished in a time-dependent manner. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：277 / 282

页数：6

共 12 条

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[2] Light microscopy and magnetic resonance characterization of a DMSA-coated magnetic fluid in mice [J].