New azidometalkojates and their biological activity

被引：58

作者：

Hudecova, D

Jantova, S

Melnik, M

Uher, M

机构：

[1] SLOVAK UNIV TECHNOL BRATISLAVA, FAC CHEM TECHNOL, DEPT INORGAN CHEM, BRATISLAVA 81237, SLOVAKIA

[2] SLOVAK UNIV TECHNOL BRATISLAVA, FAC CHEM TECHNOL, DEPT ORGAN CHEM, BRATISLAVA 81237, SLOVAKIA

来源：

FOLIA MICROBIOLOGICA | 1996年 / 41卷 / 06期

关键词：

D O I：

10.1007/BF02814660

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Azidometalkojates of the general formula MX(2) (M = Cu, Mn, Mg, Zn or Ni and X = 5-hydroxy-2-azidomethyl-4H-pyran-4-one) were prepared and tested for antibacterial, antifungal and cytotoxic effects. The mangan and zinc derivatives are not active against any the tested microorganisms. A weak antibacterial activity was found with the copper derivative. The strongest antifungal effects were shown by the nickel derivative while the highest cytotoxic effect on HeLa cells was manifested by the zinc derivative.

引用

页码：473 / 476

页数：4

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