Prevalence of positive anticardiolipin antibody in benign infantile convulsion

被引:13
作者
Yoshimura, K
Konishi, T
Kotani, H
Wakiguchi, H
Kurashige, T
机构
[1] Tosa Municipal Hosp, Dept Pediat, Tosa, Kochi 7811101, Japan
[2] Nagaoka Ryouikuen, Dept Pediat, Niigata, Japan
[3] Natl Sanatorium Higashi Kochi Hosp, Dept Pediat, Kochi, Japan
[4] Kochi Hosp, Sch Med, Dept Pediat, Kochi, Japan
关键词
benign infantile convulsion; epilepsy; anticardiolipin antibody;
D O I
10.1016/S0387-7604(01)00233-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report six anticardiolipin antibody (aCL)-positive cases among 18 children with epilepsy showing various seizure types in our initial study. These six cases revealed normal coagulation tests. As three of these six cases involved benign infantile convulsion (BIC), we further investigated the high frequency of positive aCL-Immunoglobulin (Ig) G in BIC in our subsequent study of nine cases that included three cases from the previous study and an additional six BIC cases followed and/or diagnosed by co-author (T.K.). As a result, eight of nine BIC cases were positive for aCL-IgG and the values of aCL-IgG decreased over long-term observation in three of these cases. The frequency of positivity for aCL-IgG in BIC was obviously higher than that of controls. Based on these results, we suggest that some immunological responses may be responsible for the pathogenesis of BIC. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:317 / 320
页数:4
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