The German Cartilage Registry (KnorpelRegister DGOU) for Evaluation of Surgical Treatment for Cartilage Defects: Experience after Six Months Including First Demographic Data

被引：29

作者：

Niemeyer, P. ^{[1
]}

Schweigler, K. ^{[1
,2
]}

Grotejohann, B. ^{[2
]}

Maurer, J. ^{[2
]}

Angele, P. ^{[3
]}

Aurich, M. ^{[4
]}

Becher, C. ^{[5
]}

Fay, J. ^{[6
]}

Feil, R. ^{[7
]}

Fickert, S. ^{[3
]}

Fritz, J. ^{[8
]}

Hoburg, A. ^{[9
]}

Kreuz, P. ^{[10
]}

Kolombe, T. ^{[11
]}

Laskowski, J. ^{[7
]}

Luetzner, J. ^{[12
]}

Marlovits, S. ^{[13
]}

Mueller, P. E. ^{[14
]}

Niethammer, T. ^{[14
]}

Pietschmann, M. ^{[14
]}

Ruhnau, K. ^{[15
]}

Spahn, G. ^{[16
]}

Tischer, T. ^{[10
]}

Zinser, W. ^{[17
]}

Albrecht, D. ^{[18
]}

机构：

[1] Univ Freiburg Klinikum, Dept Orthopadie & Traumatol, D-79098 Freiburg, Germany

[2] Univ Freiburg Klinikum, Studienzentrum, D-79098 Freiburg, Germany

[3] Sportorthopaedicum Regensburg Straubing, Straubing, Germany

[4] Kliniken Leipziger Land, Klin Orthopad Chirurg Unfall & Handchirurg, Borna, Germany

[5] Hannover Med Sch, Orthopad Klin Annastift, Hannover, Germany

[6] Lubinus Clinicum Kiel, Kiel, Germany

[7] Kath Marienkrankenhaus, Klin Unfallchirurg Orthopadie & Handchirurg, Hamburg, Germany

[8] Orthopadisch Chirurg Zentrum, Tubingen, Germany

[9] Charite, Klin Orthopad Unfall & Wiederherstellungschirurg, Berlin, Germany

[10] Univ Klinikum Rostock, Orthopad Klin & Poliklin, Rostock, Germany

[11] DRK Krankenhaus Luckenwalde, Klin Orthopadie & Unfallchirurg, Luckenwalde, Germany

[12] Univ Klinikum Dresden, Univ Ctr Orthopadie & Unfallchirurg, Dresden, Germany

[13] Med Univ Wien, Klin Unfallchirurg, Vienna, Austria

[14] Univ Munich, Klin & Poliklin Orthopadie Phys Med & Rehabil, Munich, Germany

[15] Viktoriaklin Bochum, Fachklin Orthopadie & Orthopad Chirurg, Bochum, Germany

[16] Praxisklin Orthopadie & Unfallchirurg, Eisenach, Germany

[17] St Vinzenz Hosp, Klin Orthopadie & Unfallchirurg Sportmed & Alters, Dinslaken, Germany

[18] Klin Kronprinzenbau, Reutlingen, Germany

来源：

ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE | 2015年 / 153卷 / 01期

关键词：

cartilage defect; knee joint; registry; bone marrow stimulation; cell transplantation; AUTOLOGOUS CHONDROCYTE IMPLANTATION; ANTERIOR CRUCIATE LIGAMENT; TOTAL KNEE ARTHROPLASTY; RANDOMIZED CONTROLLED-TRIAL; NATIONAL JOINT REGISTRY; PATELLAR TENDON GRAFTS; TOTAL HIP REPLACEMENTS; HAMSTRING TENDON; MENISCAL TEAR; OSTEOARTHRITIS;

D O I：

10.1055/s-0034-1383222

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

The German Cartilage Registry (KnorpelRegister DGOU) has been introduced in October 2013 and aims on the evaluation of patients who underwent cartilage repair for symptomatic cartilage defects. It represents a nation-wide cohort study which has been introduced by the working group "Tissue Regeneration" of the Germany Society of Orthopaedic Surgery and Traumatology and is technically based upon a web-based remote data entry (RDE) system. The present article describes first experiences with the registry including patient and treatment characteristics. Between October 2013 and April 2014, a total of 230 patients who had undergone surgical cartilage repair for symptomatic full-thickness cartilage defects of the knee has been included in the German Cartilage Registry from 23 cartilage repair centres. Mean age was 37.11 years (SD 13.61) and mean defect size was 3.68 cm(2) (SD 0.23). Since the introduction of the KnorpelRegister DGOU the total number of registered patients has increased steadily up to the most recent figure of 72 patients within one month. Patients were treated mainly according to the recommended therapies. The highest percentage in therapy is represented by the bone marrow stimulation techniques (55.02%) as well as by the autologous chondrocyte transplantation (34.92%). Unlike the patient collective in the majority of prospective randomised controlled trials, the patient population within the registry shows a high proportion of patients with accompanying pathologies, with an age of more than 50 years at the time of treatment and with unfavourably assessed accompanying pathologies such as an affection of the opposite cartilage surface or a previously resected meniscus. In summary, the technical platform and forms of documentation of the KnorpelRegister DGOU have proved to be very promising within the first six months. Unlike data from other clinical trials, the previous analysis of the patients' data and therapies reflects successfully the actual medical care situation of patients with cartilage defects of the knee joint. This analysis also provides new information on subgroups of patients that have not yet been recorded in the scientific literature. This will be part of the first analysis of clinical treatment data. An expansion of the KnorpelRegister DGOU to patients with cartilage defects of the ankle and hip joints is already decided upon and initialised.

引用

页码：67 / 74

页数：8

共 39 条

[1]

The Swedish National Anterior Cruciate Ligament Register A Report on Baseline Variables and Outcomes of Surgery for Almost 18,000 Patients [J].