Genetic variation analyses by Pyrosequencing

被引：94

作者：

Langaee, T ^{[1
]}

Ronaghi, M

机构：

[1] Univ Florida, Ctr Pharmacogenom, Dept Pharm Practice, Gainesville, FL USA

[2] Stanford Univ, Stanford Genome Technol Ctr, Palo Alto, CA 94304 USA

[3] Univ Tehran, Inst Biochem & Biophys, Tehran, Iran

来源：

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 2005年 / 573卷 / 1-2期

关键词：

SNP; pyrosequencing; re-sequencing; bioluminescence; haplotyping; mutation detection luciferase;

D O I：

10.1016/j.mrfmmm.2004.07.023

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Pyrosequencing is a real-time bioluminometric technique for determination of nucleic acid sequence. Here, we review recent advances and discuss new applications of this technique. Cost reduction efforts and future potentials of this technique for large-scale genotyping applications will also be discussed. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：96 / 102

页数：7

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