Vaccine effectiveness for influenza in the elderly in welfare nursing homes during an influenza A (H3N2) epidemic

被引：13

作者：

Deguchi, Y

Takasugi, Y

Nishimura, K

机构：

[1] Osaka Prefectural Govt, Off Elderly Affairs, Chuo Ku, Osaka 5408570, Japan

[2] Osaka Prefectural Govt, Dept Social Welf, Chuo Ku, Osaka 5408570, Japan

[3] Osaka Prefectural Govt, Dept Publ Hlth, Osaka, Japan

[4] Osaka Univ, Fac Med, Grad Sch Med, Dept Paediat, Osaka 530, Japan

来源：

EPIDEMIOLOGY AND INFECTION | 2000年 / 125卷 / 02期

关键词：

D O I：

10.1017/S0950268899004410

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Influenza vaccine effect on the occurrence and severity of influenza virus infection in a population residing in nursing homes for the elderly was studied as a cohort study during an influenza A (H3N2) epidemic in Japan. Of 22 462 individuals living in 301 welfare nursing homes, 10739 voluntarily received inactivated, sub-unit trivalent influenza vaccine in a programme supported by the Osaka Prefectural Government. There were statistically significantly fewer cases of influenza, hospital admissions due to severe infection, and deaths due to influenza in the vaccinated cohort compared to the unvaccinated controls. No serious adverse reactions to vaccination were recorded. Thus influenza vaccination is effective for preventing influenza disease in persons aged 65 years and over, and should be an integral part of the care of this population residing in nursing homes.

引用

页码：393 / 397

页数：5

共 17 条

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