Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

被引：18

作者：

Dunne, MW ^{[1
]}

Khurana, C

Mohs, AA

Rodriguez, A

Arrieta, A

McLinn, S

Krogstad, JA

Blatter, M

Schwartz, R

Vargas, SL

Emparanza, P

Fernandez, P

Gooch, WM

Aspin, M

Podgore, J

Roine, I

Blumer, JL

Ehrlich, GD

Chow, J

机构：

[1] Pfizer Global Res & Dev, 50 Pequot Ave,MS6025-C2173, New London, CT 06320 USA

[2] Maya Family Med Ctr, Chicago, IL USA

[3] Hosp Nacl Ninos Dr Carlos Saenz Herrera, San Jose, Costa Rica

[4] Neeman ICIC, San Jose, Costa Rica

[5] Hosp Infantil Juan Pablo II, Guatemala City, Guatemala

[6] Childrens Hosp Orange Cty, Orange, CA USA

[7] Pediat Plus, Clovis, CA USA

[8] Childrens Hosp & Hlth Ctr, San Diego, CA USA

[9] Scottsdale Pediat Ctr, Scottsdale, AZ USA

[10] Primary Phys Res, Pittsburgh, PA USA

[11] Allegheny Singer Res Inst, Ctr Genom Sci, Pittsburgh, PA 15212 USA

[12] MCP Hahnemann Sch Med, Dept Microbiol & Immunol, Pittsburgh, PA USA

[13] Vienna Pediat Associates, Vienna, VA USA

[14] Univ Chile, Sch Med, Clin Res Grp, Santiago, Chile

[15] Ctr Med OTOMED, Santiago, Chile

[16] Univ Chile, Hosp Clin, Santiago, Chile

[17] Hosp Ninos Luis Calvo Mackenna, Santiago, Chile

[18] Hill Top Res Inc, Salt Lake City, UT USA

[19] Univ N Texas, Hlth Sci Ctr, Dept Pediat, Ft Worth, TX USA

[20] Rainbow Babies & Childrens Hosp, Cleveland, OH 44106 USA

[21] Pfizer Inc, New York, NY USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 08期

关键词：

D O I：

10.1128/AAC.47.8.2663-2665.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

引用

页码：2663 / 2665

页数：3

共 12 条

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