Purification and characterization of the antimicrobial peptide, ostricacin

被引：27

作者：

Yu, PL ^{[1
]}

Choudhury, SD ^{[1
]}

Ahrens, K ^{[1
]}

机构：

[1] Massey Univ, Coll Sci, Inst Technol & Engn, Biotechnol Grp, Palmerston North, New Zealand

来源：

BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 03期

关键词：

antimicrobial peptide; beta-defensin; ostricacin; ostrich leukocytes;

D O I：

10.1023/A:1005623806445

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An antimicrobial peptide, ostricacin-1, has been purified and characterized from ostrich leukocytes. The peptide has a mass of 4011 and contained 36 residues, including 3 intramolecular cystine disulfide bonds. Ostricacin-1 has a primary sequence homology to the beta -defensin family and was active at 6.7 mug ml(-1) against E. coli and Staphylocccus aureus in vitro.

引用

页码：207 / 210

页数：4

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