Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography

被引：17

作者：

Becker, W ^{[1
]}

Bergmann, A ^{[1
]}

Gibson, A ^{[1
]}

Everdell, N ^{[1
]}

Jennions, D ^{[1
]}

Schweige, M ^{[1
]}

Arridge, SR ^{[1
]}

Hebden, JC ^{[1
]}

机构：

[1] Becker & Hickl GmbH, D-12277 Berlin, Germany

来源：

OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE VI | 2005年 / 5693卷

关键词：

TCSPC; diffuse optical tomography; brain imaging;

D O I：

10.1117/12.589004

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We present a multi-dimensional TCSPC technique that combines multi-detector and multiplexing capability, and records fast and virtually unlimited sequences of time-of-flight distributions. The system consists of four fully parallel TCSPC channels. Each channel records simultaneously in up to eight detection channels. Up to four lasers and 32 source positions can be multiplexed. The total count rate is up to 4 x 10(7) photons per second. Time-of-flight sequences can be recorded with a resolution of 50 to 100 ms per curve. The system is operated within a single personal computer.

引用

页码：34 / 42

页数：9

共 44 条

[1]

Arridge SR, 2000, INT J IMAG SYST TECH, V11, P2, DOI 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO

[2]

2-J

[3] Time-resolved spectrophotometer for turbid media based on supercontinuum generation in a photonic crystal fiber [J].

Bassi, A ;

Swartling, J ;

D'Andrea, C ;

Pifferi, A ;

Torricelli, A ;

Cubeddu, R .

OPTICS LETTERS, 2004, 29 (20) :2405-2407

[4]

*BECK HICKL GMBH, 2003, SPC 134 SPC 830 TIM

[5]

*BECK HICKL GMBH, BHP 600 BHLP 700 NEA

[6] High-speed FLIM data acquisition by time-correlated single photon counting [J].

Becker, W ;

Bergmann, A ;

Biscotti, G ;

Koenig, K ;

Riemann, I ;

Kelbauskas, L ;

Biskup, C .

MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES IV, 2004, 5323 :27-35

[7] High count rate multichannel TCSPC for optical tomography [J].

Becker, W ;

Bergmann, A ;

Wabnitz, H ;

Grosenick, D ;

Liebert, A .

PHOTON MIGRATION, OPTICAL COHERENCE TOMOGRAPHY, AND MICROSCOPY, 2001, 4431 :249-254

[8] Time-resolved detection and identification of single analyte molecules in microcapillaries by time-correlated single-photon counting (TCSPC) [J].

Becker, W ;

Hickl, H ;

Zander, C ;

Drexhage, KH ;

Sauer, M ;

Siebert, S ;

Wolfrum, J .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1999, 70 (03) :1835-1841

[9] Fluorescence lifetime imaging by time-correlated single-photon counting [J].

Becker, W ;

Bergmann, A ;

Hink, MA ;

König, K ;

Benndorf, K ;

Biskup, C .

MICROSCOPY RESEARCH AND TECHNIQUE, 2004, 63 (01) :58-66

[10] Multi-wavelength TCSPC lifetime imaging [J].

Becker, W ;

Bergmann, A ;

Biskup, C ;

Zimmer, T ;

Klöcker, N ;

Benndorf, K .

MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES II, 2002, 4620 :79-84

← 1 2 3 4 5 →