Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia

被引：223

作者：

Luperchio, SA

Schauer, DB

机构：

[1] MIT, Div Bioengn & Environm Hlth, Cambridge, MA 02139 USA

[2] MIT, Div Comparat Med, Cambridge, MA 02139 USA

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 04期

关键词：

Citrobacter rodentium; epithelial hyperplasia; attaching and effacing;

D O I：

10.1016/S1286-4579(01)01387-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Here we review the history, clinical significance, pathology and molecular pathogenesis of Citrobacter rodentium, the causative agent of transmissible murine colonic hyperplasia. C. rodentium serves as an important model pathogen for investigating the mechanisms controlling attaching and effacing pathology, epithelial hyperproliferation, and tumor promotion in the distal colon of the mouse. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：333 / 340

页数：8

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