GeneNote: whole genome expression profiles in normal human tissues

被引:138
作者
Shmueli, O [1 ]
Horn-Saban, S
Chalifa-Caspi, V
Shmoish, M
Ophir, R
Benjamin-Rodrig, H
Safran, M
Domany, E
Lancet, D
机构
[1] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Dept Biol Serv, IL-76100 Rehovot, Israel
[3] Weizmann Inst Sci, Dept Phys Complex Syst, IL-76100 Rehovot, Israel
关键词
microarray; transcriptome; expression profile; normal human tissues; GeneCards;
D O I
10.1016/j.crvi.2003.09.012
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A novel data set, GeneNote (Gene Normal Tissue Expression), was produced to portray complete gene expression profiles in healthy human tissues using the Affymetrix GeneChip HG-U95 set, which includes 62 839 probe-sets. The hybridization intensities of two replicates were processed and analyzed to yield the complete transcriptome for twelve human tissues. Abundant novel information on tissue specificity provides a baseline for past and future expression studies related to diseases. The data is posted in GeneNote (http://genecards.weizmann.ac.il/genenote/), a widely used compendium of human genes (http://bioinfo.weizmann.ac.il/genecards). (C) 2003 Academie des sciences. Published by Elsevier SAS. All rights reserved.
引用
收藏
页码:1067 / 1072
页数:6
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