Genetic diversity of a canine coronavirus detected in pups with diarrhoea in Italy

被引：106

作者：

Pratelli, A

Martella, V

Decaro, N

Tinelli, A

Camero, M

Cirone, F

Elia, G

Cavalli, A

Corrente, M

Greco, G

Buonavoglia, D

Gentile, M

Tempesta, M

Buonavoglia, C

机构：

[1] Fac Vet Med Bari, Dept Anim Hlth & Wellbeing, I-70010 Bari, Italy

[2] Polo Univ Annunziata, Fac Vet Med Messina, Dept Vet Publ Hlth, Messina, Italy

[3] IRCCS Saverio Bellis, Serv Med Genet, Bari, Italy

来源：

JOURNAL OF VIROLOGICAL METHODS | 2003年 / 110卷 / 01期

关键词：

coronavirus; dog; genotype; diversity;

D O I：

10.1016/S0166-0934(03)00081-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The sequence of the S gene of a field canine coronavirus (CCoV), strain Elmo/02, revealed low nucleotide (61%) and amino acid (54%) identity to reference CCoV strains. The highest correlation (77% nt and 81.7% aa) was found with feline coronavirus type I. A PCR assay for the S gene of strain Elmo/02 detected analogous CCoVs of different geographic origin, all which exhibited at least 92-96% nucleotide identity to each other and to strain Elmo/02. The evident genetic divergence between the reference CCoV strains and the newly identified Elmo/02-like CCoVs strongly suggests that a novel genotype of CCoV is widespread in the dog population. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：9 / 17

页数：9

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