One-pot synthesis of multivalent arrays of mannose mono- and disaccharides

被引:92
作者
Hayes, W
Osborn, HMI [1 ]
Osborne, SD
Rastall, RA
Romagnoli, B
机构
[1] Univ Reading, Sch Chem, Reading RG6 6AD, Berks, England
[2] Univ Reading, Sch Food Biosci, Reading RG6 6AD, Berks, England
关键词
anti-infective; E; coli; S; suis; mannose; fimbriae; dendrimer;
D O I
10.1016/j.tet.2003.08.011
中图分类号
O62 [有机化学];
学科分类号
070303 [有机化学]; 081704 [应用化学];
摘要
The synthesis of a selection of multivalent arrays of mannose mono- and disaccharides, that are of potential use as anti-infective agents against enterobacteria infections, is described. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7983 / 7996
页数:14
相关论文
共 32 条
[1]
Synthesis and biological evaluation of α-D-mannopyranoside-containing dendrimers [J].
Ashton, PR ;
Hounsell, EF ;
Jayaraman, N ;
Nilsen, TM ;
Spencer, N ;
Stoddart, JF ;
Young, M .
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (10) :3429-3437
[2]
BLOCK K, 1974, J CHEM SOC P2, P293
[3]
A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A [J].
Corbell, JB ;
Lundquist, JJ ;
Toone, EJ .
TETRAHEDRON-ASYMMETRY, 2000, 11 (01) :95-111
[4]
2-BROMOETHYL GLYCOSIDES - SYNTHESIS AND CHARACTERIZATION [J].
DAHMEN, J ;
FREJD, T ;
GRONBERG, G ;
LAVE, T ;
MAGNUSSON, G ;
NOORI, G .
CARBOHYDRATE RESEARCH, 1983, 116 (02) :303-307
[5]
Synthesis of glycoproteins [J].
Davis, BG .
CHEMICAL REVIEWS, 2002, 102 (02) :579-601
[6]
ELLIS GP, 1955, ADV CARBOHYD CHEM, V10, P95
[7]
CARBOHYDRATE-BINDING SITES OF THE MANNOSE-SPECIFIC FIMBRIAL LECTINS OF ENTEROBACTERIA [J].
FIRON, N ;
OFEK, I ;
SHARON, N .
INFECTION AND IMMUNITY, 1984, 43 (03) :1088-1090
[8]
SYNTHESIS OF ALIPHATIC O-DIMANNOSYL AMINO-ACID BUILDING-BLOCKS FOR SOLID-PHASE ASSEMBLY OF GLYCOPEPTIDE LIBRARIES [J].
FRANZYK, H ;
MELDAL, M ;
PAULSEN, H ;
BOCK, K .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1995, (22) :2883-2898
[9]
Stereospecific synthesis and characterization of aminoglycoside ligands from diethylenetriamine [J].
Gaucher, SP ;
Pedersen, SF ;
Leary, JA .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (11) :4012-4015
[10]
One-pot synthesis of multivalent arrays of mannose mono- and disaccharides [J].
Hayes, W ;
Osborn, HMI ;
Osborne, SD ;
Rastall, RA ;
Romagnoli, B .
TETRAHEDRON LETTERS, 2002, 43 (43) :7683-7685