B1 cells: similarities and differences with other B cell subsets

被引:290
作者
Martin, F [1 ]
Kearney, JF [1 ]
机构
[1] Univ Alabama Birmingham, Dept Microbiol, Div Dev & Clin Immunol, Birmingham, AL 35294 USA
关键词
D O I
10.1016/S0952-7915(00)00204-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Since their discovery, B1 B cells' origins and developmental pathways have eluded characterization. In the past year, focus on B1 B cells has shifted dramatically from developmental to functional aspects of these cells. Most advances have been made in describing the physiological activities of B1 cells, including their migration, activation by antigen and role in both autoimmunity and malignancy.
引用
收藏
页码:195 / 201
页数:7
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