A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healing

被引：85

作者：

Li, M ^{[1
]}

Ke, HZ ^{[1
]}

Qi, H ^{[1
]}

Healy, DR ^{[1
]}

Li, Y ^{[1
]}

Crawford, DT ^{[1
]}

Paralkar, VM ^{[1
]}

Owen, TA ^{[1
]}

Cameron, KO ^{[1
]}

Lefker, BA ^{[1
]}

Brown, TA ^{[1
]}

Thompson, DD ^{[1
]}

机构：

[1] Pfizer Global Res & Dev, Groton Labs, Dept Cardiovasc & Metab Dis, Groton, CT USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2003年 / 18卷 / 11期

关键词：

prostaglandin E-2; EP2 receptor agonist; local bone formation; fracture healing;

D O I：

10.1359/jbmr.2003.18.11.2033

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

CP-533,536, a newly discovered, non-prostanoid EP2 receptor-selective PGE(2) agonist, stimulates local bone formation and enhances fracture healing in rat models.

引用

页码：2033 / 2042

页数：10

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