Acute hepatitis E of a man who consumed wild boar meat prior to the onset of illness in Nagasaki, Japan - Case report
被引:118
作者:
Masuda, JI
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Masuda, JI
Yano, K
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WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, JapanWHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Yano, K
[1
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Tamada, Y
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Tamada, Y
Takii, Y
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Takii, Y
Ito, M
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Ito, M
Omagari, K
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Omagari, K
Kohno, S
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机构:WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
Kohno, S
机构:
[1] WHO, Collaborating Ctr Res & Reference Viral Hepatitis, NHO, Natl Med Ctr,Clin Res Ctr, Omura, Japan
[2] Nagasaki Municipal Med Ctr, Nagasaki, Japan
[3] Nagasaki Univ, Sch Med, Dept Internal Med 2, Nagasaki 852, Japan
Zoonotic infection of hepatitis E virus (HEV) has been suggested. To date, pigs, deer, and wild boar have been implicated as reservoirs of HEV in Japan. However, it is not known to what extent zoonotic transmission of HEV play roles of causing HEV transmission. In the present report, we describe a case of acute hepatitis E in which a transmission of HEV by a zoonotic transmission is strongly suggested. The patient had eaten grilled wild boar meat 59 days prior to onset of acute hepatitis. Although the meat was not stored, one of the two people who ate boar meat with the patient at the same time showed high levels of HEV-IgM and -IgG and normal levels of liver enzymes, suggesting a subclinical infection of HEV. Accumulating evidence suggests that eating wild boars is associated with a high risk of acquiring hepatitis E infection. (c) 2005 Elsevier B.V. All rights reserved.