Complex regulation of multiple cytohesin-like genes in murine tissues and cells

被引：44

作者：

Kim, HS ^{[1
]}

Chen, YL ^{[1
]}

Lonai, P ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel

来源：

FEBS LETTERS | 1998年 / 433卷 / 03期

关键词：

cytohesin; pleckstrin domain; Sec7; domain; specific expression; reverse transcription polymerase chain reaction;

D O I：

10.1016/S0014-5793(98)00937-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three cytohesin-like cDNA molecules were isolated from marine ES cell derived embryoid bodies. The genomic structure of one of the three, CLM2, has been determined and transcriptional variants of each were isolated from a mouse brain cDNA library. The relative expression patterns of CLM1, 2, 3 and their transcriptional alternatives were determined by RT-PCR, nucleotide sequencing and RNA blotting, Their broad distribution and cell and tissue specific expression patterns suggest complex regulation during development and in the adult. (C) 1998 Federation of European Biochemical Societies.

引用

页码：312 / 316

页数：5

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