Silyloxy-cope rearrangement of chiral aldol adducts

被引：26

作者：

Black, WC

Giroux, A

Greidanus, G

机构：

[1] Merck Frosst Ctr. for Therapeut. R., Pointe-Claire-Dorval, Que. H9R 4P8

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 26期

关键词：

D O I：

10.1016/0040-4039(96)00904-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The silyloxy-Cope rearrangement of a chiral 1,5-diene generated from aldol condensation proceeds in high yield and selectivity under mild thermal conditions to generate a new stereocenter five atoms removed from the chiral auxiliary. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：4471 / 4474

页数：4

共 7 条

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[6] ASYMMETRIC 1,4-ADDITION OF ORGANOCUPRATES TO CHIRAL ALPHA,BETA-UNSATURATED N-ACYL-4-PHENYL-2-OXAZOLIDINONES - A NEW APPROACH TO THE SYNTHESIS OF CHIRAL BETA-BRANCHED CARBOXYLIC-ACIDS
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[7] WILLIAMS DR, 1994, TETRAHEDRON LETT, P5113

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