Muscle reconstruction in reconstructive surgery: soft tissue repair and long bone reconstruction

被引:217
作者
Masquelet, AC [1 ]
机构
[1] Hop Avicenne, Dept Orthopaed & Reconstruct Surg, F-93009 Bobigny, France
关键词
bone reconstruction; growth factors; cancellous bone graft; pseudosynovial membrane;
D O I
10.1007/s00423-003-0379-1
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background. We report a series of reconstructions of long bone defects in 35 patients. Bone defects ranged from 5.0 to 25.0 cm. Method. Reconstruction was performed in two stages. The first stage was the insertion into the defect of a cement spacer, which was responsible for the formation of a pseudosynovial membrane. A soft tissue repair employing a flap was done in the same operating time in 28 cases. The second stage was the reconstruction of the bone defect by a large, fresh, autologous cancellous bone graft. Results. The membrane induced by the spacer prevents the resorption of the graft and favours its revascularisation and its corticalisation. Experimental study has also shown that the membrane plays the role of an 'in situ growth-factors delivery system'. Conclusion. In weight-bearing diaphyseal segments normal walking was possible at 8.5 months on average.
引用
收藏
页码:344 / 346
页数:3
相关论文
共 18 条
[1]
CATTANEO R, 1992, CLIN ORTHOP RELAT R, V280, P143
[2]
CHANG N, 1982, PLAST RECONSTR SURG, V70, P1
[3]
COOK SD, 2000, CLIN ORTHOP RELAT R, V381, P47
[4]
Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation [J].
Deckers, MML ;
Karperien, M ;
van der Bent, C ;
Yamashita, T ;
Papapoulos, SE ;
Löwik, CWGM .
ENDOCRINOLOGY, 2000, 141 (05) :1667-1674
[5]
EXPERIMENTAL COMPARISON OF BONE REVASCULARIZATION BY MUSCULOCUTANEOUS AND CUTANEOUS FLAPS [J].
FISHER, J ;
WOOD, MB .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1987, 79 (01) :81-90
[6]
Friedlaender GE, 2001, J BONE JOINT SURG AM, V83A, pS151
[7]
VASCULARIZED BONE TRANSFER [J].
HAN, CS ;
WOOD, MB ;
BISHOP, AT ;
COONEY, WP .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1992, 74A (10) :1441-1449
[9]
IRONS GB, 1984, ORTHOP CLIN N AM, V15, P473
[10]
Masquelet A C, 2000, Ann Chir Plast Esthet, V45, P346