Broad-spectrum mildew resistance in Arabidopsis thaliana mediated by RPW8

被引:370
作者
Xiao, SY [1 ]
Ellwood, S [1 ]
Calis, O [1 ]
Patrick, E [1 ]
Li, TX [1 ]
Coleman, M [1 ]
Turner, JG [1 ]
机构
[1] Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England
关键词
D O I
10.1126/science.291.5501.118
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Plant disease resistance (R) genes control the recognition of specific pathogens and activate subsequent defense responses. We show that the Arabidopsis thaliana Locus RESISTANCE TO POWDERY MILDEW8 (RPW8) contains two naturally polymorphic, dominant R genes, RPW8.1 and RPW8.2, which individually control resistance to a broad range of powdery mildew pathogens. Although the predicted RPW8.1 and RPW8.2 proteins are different from the previously characterized R proteins, they induce Localized, salicylic acid-dependent defenses similar to those induced by R genes that control specific resistance. Apparently, broad-spectrum resistance mediated by RPW8 uses the same mechanisms as specific resistance.
引用
收藏
页码:118 / 120
页数:3
相关论文
共 24 条
[1]   Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis [J].
Aarts, N ;
Metz, M ;
Holub, E ;
Staskawicz, BJ ;
Daniels, MJ ;
Parker, JE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (17) :10306-10311
[2]   Comparison of Erysiphe cichoracearum and E-cruciferarum and a survey of 360 Arabidopsis thaliana accessions for resistance to these two powdery mildew pathogens [J].
Adam, L ;
Ellwood, S ;
Wilson, I ;
Saenz, G ;
Xiao, S ;
Oliver, RP ;
Turner, JG ;
Somerville, S .
MOLECULAR PLANT-MICROBE INTERACTIONS, 1999, 12 (12) :1031-1043
[3]   Signaling in plant-microbe interactions [J].
Baker, B ;
Zambryski, P ;
Staskawicz, B ;
DineshKumar, SP .
SCIENCE, 1997, 276 (5313) :726-733
[4]   Map positions of 47 Arabidopsis sequences with sequence similarity to disease resistance genes [J].
Botella, MA ;
Coleman, MJ ;
Hughes, DE ;
Nishimura, MT ;
Jones, JDG ;
Somerville, SC .
PLANT JOURNAL, 1997, 12 (05) :1197-1211
[5]   The barley mlo gene: A novel control element of plant pathogen resistance [J].
Buschges, R ;
Hollricher, K ;
Panstruga, R ;
Simons, G ;
Wolter, M ;
Frijters, A ;
vanDaelen, R ;
vanderLee, T ;
Diergaarde, P ;
Groenendijk, J ;
Topsch, S ;
Vos, P ;
Salamini, F ;
Schulze-Lefert, P .
CELL, 1997, 88 (05) :695-705
[6]   Floral dip:: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana [J].
Clough, SJ ;
Bent, AF .
PLANT JOURNAL, 1998, 16 (06) :735-743
[7]   PIECE DE RESISTANCE - NOVEL CLASSES OF PLANT-DISEASE RESISTANCE GENES [J].
DANGL, JL .
CELL, 1995, 80 (03) :363-366
[8]   Plant disease resistance genes [J].
HammondKosack, KE ;
Jones, JDG .
ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY, 1997, 48 :575-607
[9]   Evidence for a role of the N terminus and leucine-rich repeat region of the Mi gene product in regulation of localized cell death [J].
Hwang, CF ;
Bhakta, AV ;
Truesdell, GM ;
Pudlo, WM ;
Williamson, VM .
PLANT CELL, 2000, 12 (08) :1319-1329
[10]   GENE-FOR-GENE COMPLEMENTARITY IN PLANT-PATHOGEN INTERACTIONS [J].
KEEN, NT .
ANNUAL REVIEW OF GENETICS, 1990, 24 :447-463