Bioinorganic reaction mechanisms: From high-valent iron to bioorganometallic chemistry

被引：17

作者：

Slep, LD ^{[1
]}

Neese, F ^{[1
]}

机构：

[1] Max Planck Inst Strahlenchem, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 26期

关键词：

bioinorganic chemistry; cyanide ligands; iron complexes; metalloproteins; oxygen activation;

D O I：

10.1002/anie.200301649

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Important aspects of the mechanisms of fundamental bioinorganic reactions have been revealed in recent studies, which have shed light on the structure and properties of high-valent nonheme Fe centers (left structure) as well as on the biosynthetic formation of the Fe-CN bond in Ni-Fe hydrogenases (right).

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页码：2942 / 2945

页数：4

相关论文

共 20 条

[1] INFRARED-DETECTABLE GROUPS SENSE CHANGES IN CHARGE-DENSITY ON THE NICKEL CENTER IN HYDROGENASE FROM CHROMATIUM-VINOSUM [J].

BAGLEY, KA ;

DUIN, EC ;

ROSEBOOM, W ;

ALBRACHT, SPJ ;

WOODRUFF, WH .

BIOCHEMISTRY, 1995, 34 (16) :5527-5535

[2] A synthetic model for the putative FeIV2O2 diamond core of methane monooxygenase intermediate Q [J].

Costas, M ;

Rohde, JU ;

Stubna, A ;

Ho, RYN ;

Quaroni, L ;

Münck, E ;

Que, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (51) :12931-12932

[3] Single crystal EPR studies of the reduced active site of [NiFe] hydrogenase from Desulfiovibrio vulgaris Miyazaki F [J].

Foerster, S ;

Stein, M ;

Brecht, M ;

Ogata, H ;

Higuchi, Y ;

Lubitz, W .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (01) :83-93

[4] Mononuclear (nitrido)iron(V) and (oxo)iron(IV) complexes via photolysis of [(cyclam-acetato)FeIII(N3)]+ and ozonolysis of [(cyclam-acetato)FeIII(O3SCF3)]+ in water/acetone mixtures [J].

Grapperhaus, CA ;

Mienert, B ;

Bill, E ;

Weyhermüller, T ;

Wieghardt, K .

INORGANIC CHEMISTRY, 2000, 39 (23) :5306-5317

[5] Crystal structure of a synthetic high-valent complex with an Fe2(μ-O)2 diamond core.: Implications for the core structures of methane monooxygenase intermediate Q and ribonucleotide reductase intermediate X [J].

Hsu, HF ;

Dong, YH ;

Shu, LJ ;

Young, VG ;

Que, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (22) :5230-5237

[6] Electronic structure and reactivity of low-spin Fe(III)-hydroperoxo complexes: Comparison to activated bleomycin [J].

Lehnert, N ;

Neese, F ;

Ho, RYN ;

Que, L ;

Solomon, EI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (36) :10810-10822

[7] Electronic structure of high-spin iron(III)-alkylperoxo complexes and its relation to low-spin analogues: Reaction coordinate of O-O bond homolysis [J].

Lehnert, N ;

Ho, RYN ;

Que, L ;

Solomon, EI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (51) :12802-12816

[8] O2 activation by nonheme iron complexes:: A monomeric Fe(III)-oxo complex derived from O2 [J].

MacBeth, CE ;

Golombek, AP ;

Young, VG ;

Yang, C ;

Kuczera, K ;

Hendrich, MP ;

Borovik, AS .

SCIENCE, 2000, 289 (5481) :938-941

[9] Photolysis of cis- and trans-[FeIII(cyclam)(N3)2]+ complexes:: Spectroscopic characterization of a nitridoiron(V) species [J].

Meyer, K ;

Bill, E ;

Mienert, B ;

Weyhermüller, T ;

Wieghardt, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (20) :4859-4876

[10] Electronic structure of activated bleomycin: Oxygen intermediates in heme versus non-heme iron [J].

Neese, F ;

Zaleski, JM ;

Zaleski, KL ;

Solomon, EI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (47) :11703-11724