A single oral administration of conjugated linoleic acid enhanced energy metabolism in mice

被引：55

作者：

Ohnuki, K ^{[1
]}

Haramizu, S ^{[1
]}

Oki, K ^{[1
]}

Ishihara, K ^{[1
]}

Fushiki, T ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Agr, Dept Appl Life Sci, Nutr Chem Lab, Kyoto 6068502, Japan

来源：

LIPIDS | 2001年 / 36卷 / 06期

关键词：

D O I：

10.1007/s11745-001-0760-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We investigated the effect of a single oral administration of conjugated linoleic acid (CLA) on energy metabolism in mice. Male Std ddY mice were orally administered CLA (5 mL/kg weight) or linoleic acid (5 mL/kg weight) (both solutions at concentrations of 73.5%) as a control. Oxygen consumption was significantly greater in the CLA-administered mice than in the control mice. Respiratory quotient was slightly lower in the CLA-administered mice than in the control mice. We calculated fat and carbohydrate oxidation from oxygen consumption and respiratory quotient. Fat oxidation in the CLA-administered mice was significantly higher than in the control mice, and there was no difference in carbohydrate oxidation. Serum concentrations of noradrenalin and adrenalin in the CLA administered mice were significantly higher than in the control mice. These results suggested that CLA enhanced sympathetic nervous activity and energy metabolism.

引用

页码：583 / 587

页数：5

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