Molecular radio jamming: Autoinducer analogs

被引：9

作者：

Fast, W ^{[1
]}

机构：

[1] Univ Texas, Coll Pharm, Div Med Chem, Austin, TX 78712 USA

[2] Univ Texas, Grad Program Biochem, Austin, TX 78712 USA

[3] Univ Texas, Grad Program Mol Biol, Austin, TX 78712 USA

来源：

CHEMISTRY & BIOLOGY | 2003年 / 10卷 / 01期

关键词：

D O I：

10.1016/S1074-5521(03)00005-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Synthesis of an N-acyl-homoserine lactone (N-acyl-HSL) analog library yields agonists and antagonists of the Pseudomonas aeruginosa quorum-sensing system. Active compounds also reveal heterogeneity in the lactone ring binding pockets of N-acyl-HSL-activated transcription factors.

引用

页码：1 / 2

页数：2

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