Meiosis: When even two is a crowd

被引：25

作者：

van Veen, JE ^{[1
]}

Hawley, RS ^{[1
]}

机构：

[1] Stowers Inst Med Res, Kansas City, MO 64110 USA

来源：

CURRENT BIOLOGY | 2003年 / 13卷 / 21期

关键词：

SYNAPTONEMAL COMPLEX LENGTH; CAENORHABDITIS-ELEGANS; CROSSING-OVER; X-CHROMOSOME; C-ELEGANS; INTERFERENCE; EXCHANGE; YEAST;

D O I：

10.1016/j.cub.2003.10.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies in Caenorhabditis elegans show that crossover interference, which usually limits the number of exchanges per meiotic bivalent to just 'one', requires the continuity of both homologs. One 'function' of crossover interference may be the prevention of crossover events that might not effectively hold homologs together.

引用

收藏

页码：R831 / R833

页数：3

相关论文

共 19 条

[1]

Albertson D., 1997, C ELEGANS, P47

[2] Segregation of holocentric chromosomes at meiosis in the nematode, Caenorhabditis elegans [J].

Albertson, Donna G. ;

Thomson, J. Nichol .

CHROMOSOME RESEARCH, 1993, 1 (01) :15-26

[3] Meiotic cohesion requires accumulation of ORD on chromosomes before condensation [J].

Balicky, EM ;

Endres, MW ;

Lai, C ;

Bickel, SE .

MOLECULAR BIOLOGY OF THE CELL, 2002, 13 (11) :3890-3900

[4]

BRENNER S, 1974, GENETICS, V77, P71

[5]

DEMBURG, 2001, J CELL BIOL, V153, pF33

[6] Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae [J].

Gerton, JL ;

DeRisi, J ;

Shroff, R ;

Lichten, M ;

Brown, PO ;

Petes, TD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) :11383-11390

[7]

HAWLEY RS, 2002, ADV GENETIC ANAL

[8] Chromosome-wide control of meiotic crossing over in C-elegans [J].

Hillers, KJ ;

Villeneuve, AM .

CURRENT BIOLOGY, 2003, 13 (18) :1641-1647

[9] HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes [J].

Howe, M ;

McDonald, KL ;

Albertson, DG ;

Meyer, BJ .

JOURNAL OF CELL BIOLOGY, 2001, 153 (06) :1227-1238

[10] Meiosis: How could it work? [J].

Kleckner, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (16) :8167-8174