Chitosan as antimicrobial agent: Applications and mode of action

被引：2204

作者：

Rabea, EI

Badawy, MET

Stevens, CV

Smagghe, G

Steurbaut, W

机构：

[1] Univ Ghent, Fac Agr & Appl Biol Sci, Dept Crop Protect, B-9000 Ghent, Belgium

[2] Univ Ghent, Fac Agr & Appl Biol Sci, Dept Organ Chem, B-9000 Ghent, Belgium

来源：

BIOMACROMOLECULES | 2003年 / 4卷 / 06期

关键词：

D O I：

10.1021/bm034130m

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chitosan, a hydrophilic biopolymer industrially obtained by N-deacetylation of chitin, can be applied as an antimicrobial agent. The current review of 129 references describes the biological activity of several chitosan derivatives and the modes of action that have been postulated in the literature. It highlights the applications of chitosan as an antimicrobial agent against fungi, bacteria, and viruses and as an elicitor of plant defense mechanisms.

引用

页码：1457 / 1465

页数：9

共 132 条

[1] Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads [J].