Calcium

被引:55
作者
Evenas, J [1 ]
Malmendal, A [1 ]
Forsen, S [1 ]
机构
[1] Lund Univ, S-22100 Lund, Sweden
关键词
D O I
10.1016/S1367-5931(98)80072-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ca2+ is involved in an intriguing variety of different biological events. The rapid development of techniques such as region-or organelle-directed fluorescent probes and laser scanning confocal microscopy for studying cellular biological events at a molecular level provides us with a rich daily intake of new results. While detailed three-dimensional structures of many intracellular and extracellular Ca2+-binding proteins have become available, structural information on key membrane proteins is still tacking. An integrated picture of the molecular events behind the multifunctional roles of Ca2+ in biological systems is still pending.
引用
收藏
页码:293 / 302
页数:10
相关论文
共 100 条
[1]   Activation and inactivation of Ca2+ release by NAADP(+) [J].
Aarhus, R ;
Dickey, DM ;
Graeff, RM ;
Gee, KR ;
Walseth, TF ;
Lee, HC .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (15) :8513-8516
[2]   SOURCE OF NUCLEAR CALCIUM SIGNALS [J].
ALLBRITTON, NL ;
OANCEA, E ;
KUHN, MA ;
MEYER, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) :12458-12462
[3]   RANGE OF MESSENGER ACTION OF CALCIUM-ION AND INOSITOL 1,4,5-TRISPHOSPHATE [J].
ALLBRITTON, NL ;
MEYER, T ;
STRYER, L .
SCIENCE, 1992, 258 (5089) :1812-1815
[4]   THE NUCLEUS IS INSULATED FROM LARGE CYTOSOLIC CALCIUM-ION CHANGES [J].
ALMOHANNA, FA ;
CADDY, KWT ;
BOLSOVER, SR .
NATURE, 1994, 367 (6465) :745-750
[5]   Structural basis for the negative allostery between Ca2+- and Mg2+-binding in the intracellular Ca2+-receptor calbindin D-9k [J].
Andersson, M ;
Malmendal, A ;
Linse, S ;
Ivarsson, I ;
Forsen, S ;
Svensson, LA .
PROTEIN SCIENCE, 1997, 6 (06) :1139-1147
[6]   Mitochondrial participation in the intracellular Ca2+ network [J].
Babcock, DF ;
Herrington, J ;
Goodwin, PC ;
Park, YB ;
Hille, B .
JOURNAL OF CELL BIOLOGY, 1997, 136 (04) :833-844
[7]   Elementary and global aspects of calcium signalling [J].
Berridge, MJ .
JOURNAL OF PHYSIOLOGY-LONDON, 1997, 499 (02) :291-306
[8]   Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor [J].
Blacklow, SC ;
Kim, PS .
NATURE STRUCTURAL BIOLOGY, 1996, 3 (09) :758-762
[9]   Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes [J].
Blanchard, H ;
Grochulski, P ;
Li, Y ;
Arthur, JSC ;
Davies, PL ;
Elce, JS ;
Cygler, M .
NATURE STRUCTURAL BIOLOGY, 1997, 4 (07) :532-538
[10]   CALCIUM-IONS AS EXTRACELLULAR MESSENGERS [J].
BROWN, EM ;
VASSILEV, PM ;
HEBERT, SC .
CELL, 1995, 83 (05) :679-682