Development of a brief scale of everyday functioning in persons with serious mental illness

被引:292
作者
Mausbach, Brent T.
Harvey, Phillip D.
Goldman, Sherry R.
Jeste, Dilip V.
Patterson, Thomas L.
机构
[1] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
[2] CUNY Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA
[3] Dept Vet Affairs, VISN 22 MIRECC, Washington, DC 20420 USA
关键词
functional capacity; schizophrenia; independence; psychotherapy;
D O I
10.1093/schbul/sbm014
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
We developed and tested the validity of a brief scale to assess everyday functioning in persons with serious mental illness. Asample of 434 adults with schizophrenia or schizoaffective disorder were administered the University of California, San Diego, Performance-Based Skills Assessment (UPSA), which assesses functional skills in 5 areas of life functioning (eg, finances and planning). Through use of factor analysis, we developed the UPSA-Brief, which consists of 2 subscales ( communication and financial) from the original UPSA. UPSA-Brief scores were correlated with cognitive functioning, symptoms of psychosis, age, and education. We further tested the sensitivity and specificity of the UPSA-Brief for predicting residential independence using receiver- operating characteristic (ROC) curves. Finally, sensitivity to change was assessed through comparison of 2 interventions for improving UPSA-Brief scores. UPSA-Brief scores were highly correlated with scores on the full version of the UPSA (r = 5.91), with overall cognitive functioning ( r = 5.57), and with negative symptoms (r = -.32). The discriminant validity of the UPSA-Brief was adequate ( ROC area under the curve [AUC] = 0.73; 95% confidence interval [CI]: 0.67-0.78), with greatest dichotomization for the UPSA-Brief at a cutoff score of 60. The UPSA-Brief was significantly better than the Dementia Rating Scale, Positive and Negative Syndromes Scale positive, and Positive and Negative Syndromes Scale negative at predicting residential independence (all P values <.05). Participants receiving a behavioral intervention also improved significantly compared with a support condition ( P = .023). The UPSA-Brief has adequate psychometric properties, predicts residential independence, is sensitive to change, and requires only 10-15 minutes to administer. Therefore, the UPSA-Brief may be a useful performance-based functional outcome scale.
引用
收藏
页码:1364 / 1372
页数:9
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