The 1995 Walter Hubert lecture - Molecular epidemiology of human cancer: Insights from the mutational analysis of the p53 tumour-suppressor gene

被引：109

作者：

Harris, CC

机构：

[1] Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, MD 20892-4255

来源：

BRITISH JOURNAL OF CANCER | 1996年 / 73卷 / 03期

关键词：

cancer susceptibility genes; cancer risk assessment; aflatoxin B-1; ultraviolet light; liver cancer; skin cancer; HEPATITIS-B VIRUS; WILD-TYPE P53; HUMAN HEPATOCELLULAR-CARCINOMA; TATA-BINDING PROTEIN; TRANSCRIPTIONAL ACTIVATION; X-PROTEIN; DNA; ONCOGENE; GROWTH; TRANSACTIVATOR;

D O I：

10.1038/bjc.1996.47

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

收藏

页码：261 / 269

页数：9

相关论文

共 84 条

[1] AFLATOXIN-B(1) INDUCES THE TRANSVERSION OF G-]T IN CODON 249 OF THE P53 TUMOR-SUPPRESSOR GENE IN HUMAN HEPATOCYTES [J].

AGUILAR, F ;

HUSSAIN, SP ;

CERUTTI, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (18) :8586-8590

[2] GEOGRAPHIC-VARIATION OF P53 MUTATIONAL PROFILE IN NONMALIGNANT HUMAN LIVER [J].

AGUILAR, F ;

HARRIS, CC ;

SUN, T ;

HOLLSTEIN, M ;

CERUTTI, P .

SCIENCE, 1994, 264 (5163) :1317-1319

[3] P53 BINDS SINGLE-STRANDED-DNA ENDS AND CATALYZES DNA RENATURATION AND STRAND TRANSFER [J].

BAKALKIN, G ;

YAKOVLEVA, T ;

SELIVANOVA, G ;

MAGNUSSON, KP ;

SZEKELY, L ;

KISELEVA, E ;

KLEIN, G ;

TERENIUS, L ;

WIMAN, KG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (01) :413-417

[4] SUPPRESSION OF HUMAN COLORECTAL-CARCINOMA CELL-GROWTH BY WILD-TYPE-P53 [J].

BAKER, SJ ;

MARKOWITZ, S ;

FEARON, ER ;

WILLSON, JKV ;

VOGELSTEIN, B .

SCIENCE, 1990, 249 (4971) :912-915

[5]

BARRETT JC, 1992, PROG CLIN BIOL RES, V376, P1

[6] HEPATITIS-B VIRUS HBX PROTEIN ACTIVATES RAS-GTP COMPLEX-FORMATION AND ESTABLISHES A RAS, RAF, MAP KINASE SIGNALING CASCADE [J].

BENN, J ;

SCHNEIDER, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (22) :10350-10354

[7] ASSOCIATION BETWEEN CIGARETTE-SMOKING AND MUTATION OF THE P53 GENE IN SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK [J].

BRENNAN, JA ;

BOYLE, JO ;

KOCH, WM ;

GOODMAN, SN ;

HRUBAN, RH ;

EBY, YJ ;

COUCH, MJ ;

FORASTIERE, AA ;

SIDRANSKY, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (11) :712-717

[8] SELECTIVE G-MUTATION TO T-MUTATION OF P53 GENE IN HEPATOCELLULAR-CARCINOMA FROM SOUTHERN AFRICA [J].

BRESSAC, B ;

KEW, M ;

WANDS, J ;

OZTURK, M .

NATURE, 1991, 350 (6317) :429-431

[9]

CARIELLO NF, 1994, CANCER RES, V54, P4454

[10] A TRANSACTIVATOR FUNCTION IS GENERATED BY INTEGRATION OF HEPATITIS-B VIRUS PRES/S SEQUENCES IN HUMAN HEPATOCELLULAR-CARCINOMA DNA [J].

CASELMANN, WH ;

MEYER, M ;

KEKULE, AS ;

LAUER, U ;

HOFSCHNEIDER, PH ;

KOSHY, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (08) :2970-2974

← 1 2 3 4 5 6 7 8 9 →