TiO2 nanotubes:: photocatalyst for cancer cell killing

被引:102
作者
Kalbacova, M. [3 ]
Macak, J. M. [1 ]
Schmidt-Stein, F. [1 ]
Mierke, C. T. [2 ]
Schmuki, P. [1 ]
机构
[1] Univ Erlangen Nurnberg, Dept Mat Sci, WW LKO 4, D-91058 Erlangen, Germany
[2] Univ Erlangen Nurnberg, Ctr Med Phys & Technol, D-91052 Erlangen, Germany
[3] Charles Univ Prague, Fac Med 1, Inst Inherited Metab Disorders, Prague 12808, Czech Republic
来源
PHYSICA STATUS SOLIDI-RAPID RESEARCH LETTERS | 2008年 / 2卷 / 04期
关键词
D O I
10.1002/pssr.200802080
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The present work reports on the use of self-organized TiO2 nanotube layers for the photocatalytic killing of cancer cells. TiO2 nanotube layers with different dimensions (diameter 50 nm and 100 nm, thickness 800 nm and 1.3 mu m, respectively) were grown by anodization of Ti. Upon low dose of UV irradiation, the vitality of cancer cells cultured on these nanotube layers was significantly affected - the cells reduced their shape and size and a significant amount of the dead cells was found. These results demonstrate that self-organized TiO2 nanotube layers can be used for photo-induced cancer cell killing. (c) 2008 WILEY-VCH Veriag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:194 / 196
页数:3
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