The influence of the alloy of megaprostheses on infection rate

被引：41

作者：

Gosheger, Georg ^{[1
]}

Goetze, Christian ^{[1
]}

Hardes, Jendrik ^{[1
]}

Joosten, Uwe ^{[2
]}

Winkelmann, Winfried ^{[1
]}

von Eiff, Christof ^{[3
]}

机构：

[1] Univ Hosp Munster, Dept Orthopaed, Munster, Germany

[2] Marien Hosp, Dept Traumatol & Orthopaed Surg, Osnabruck, Germany

[3] Univ Hosp Munster, Inst Med Microbiol, Munster, Germany

来源：

JOURNAL OF ARTHROPLASTY | 2008年 / 23卷 / 06期

关键词：

megaprosthesis; tumor endoprosthesis; infection; cobalt chrome; titanium;

D O I：

10.1016/j.arth.2007.06.015

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We retrospectively reviewed 197 patients who underwent reconstruction with a megaprosthesis of the lower extremity. A cobalt-chrome alloy system was used in 77 patients and a titanium alloy system in 120 patients. The overall infection rate was 20.8% (n = 41). Separated into the 2 prosthesis systems used, all infection rate of 31.2% was found in the patients with a cobalt-chrome-alloy prosthesis and 14.2% in the titanium alloy group of patients (P < .01). Early infection occurred in 5.1% (n = 10) and late infection in 15.7% (n = 31). Selecting 2 identical subgroups for further analysis, the cobalt-chrome alloy prostheses were associated with a significantly higher infection rate, with 5 infections of 26 megaprostheses vs I infection of 36 titanium megaprostheses (P < .05).

引用

页码：916 / 920

页数：5

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