De helminths play a role in carcinogenesis?

被引：35

作者：

Herrera, LA ^{[1
]}

Ostrosky-Wegman, P ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Genet & Toxicol Ambiental, Mexico City 04510, DF, Mexico

来源：

TRENDS IN PARASITOLOGY | 2001年 / 17卷 / 04期

关键词：

D O I：

10.1016/S1471-4922(00)01942-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Chronic helminthiasis is recognized as a significant factor in cancer development in humans. However,the mechanisms by which helminths initiate and promote malignant transformation of host cells are still not understood fully, Human helminthiasis can cause genetic instability and affect inter- and intracellular communication, ultimately leading to tumour development through inflammation, modulation of the host immune system, and secretion of soluble factors that interact with host cells.

引用

页码：172 / 175

页数：4

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