Cell cycle phase duration in bone marrow cells from malnourished rats during suckling

被引：9

作者：

Gomez, JL

Campos, C

Rangel, P

Ortiz, R

机构：

[1] UNIV AUTONOMA METROPOLITANA IZTAPALAPA,DEPT CIENCIAS SALUD,MEXICO CITY 09340,DF,MEXICO

[2] UNIV NACL AUTONOMA MEXICO,INST FISIOL CELULAR,MEXICO CITY 04510,DF,MEXICO

来源：

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 1996年 / 352卷 / 1-2期

关键词：

cell cycle; generation time; protein calorie malnutrition; bone marrow; H-3]thymidine;

D O I：

10.1016/0027-5107(95)00228-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The generation time and duration of the different phases of the cell cycle were estimated in cultured bone marrow cells from malnourished and well-nourished rats during the lactation period by the percentage labeled mitosis (PLM) technique after a short pulse treatment with tritiated thymidine. The PLM were obtained in sequential analysis after every 3 h from removing labeled thymidine to 27 h of incubation. Results have shown a longer cell cycle time in cells from malnourished rats. The G(1) + 1/2M phases are sensitive to experimental severe protein malnutrition (PCM), while S and G(2) + 1/2M phases did not show any differences in duration between malnourished and well-nourished rats.

引用

页码：57 / 60

页数：4

共 13 条

[1]

[Anonymous], [No title captured]

[2] TESTICULAR MORPHOLOGY AND CELL-PROLIFERATION KINETICS OF IMMATURE GERM-CELLS AND SERTOLI CELLS IN SUCKLING UNDERNOURISHED RATS [J].