Characteristics of articular chondrocytes seeded in collagen matrices in vitro

被引：21

作者：

Nehrer, S

Breinan, HH

Ashkar, S

Shortkroff, S

Minas, T

Sledge, CB

Yannas, IV

Spector, M

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Orthoped Surg, Boston, MA 02115 USA

[2] Univ Vienna, Dept Orthoped Surg, Vienna, Austria

[3] MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[4] Childrens Hosp, Med Ctr, Boston, MA 02115 USA

[5] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

[6] Brockton W Roxbury VA Med Ctr, W Roxbury, MA 02132 USA

来源：

TISSUE ENGINEERING | 1998年 / 4卷 / 02期

关键词：

D O I：

10.1089/ten.1998.4.175

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

This study directly compared the behavior of adult human and canine and young bovine (calf) chondrocytes in porous type I and a collagen matrices. Certain characteristics of the cells varied among these groups, with the calf cells being relatively heterogeneous, There was a similar trend, however, in the behavior of the cells in the matrices with a majority of the cells in the type II sponge retaining their chondrocytic characteristics. Collagen production by chondrocytes in matrices, as assessed by SDS-PAGE, also varied with the chemistry of the matrix.

引用

页码：175 / 183

页数：9

共 29 条

[1]

Ben-Yishay A, 1995, Tissue Eng, V1, P119, DOI 10.1089/ten.1995.1.119

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