Cancer diagnosis by infrared spectroscopy: Methodological aspects

被引：39

作者：

Jackson, M ^{[1
]}

Kim, K ^{[1
]}

Tetteh, J ^{[1
]}

Mansfield, JR ^{[1
]}

Dolenko, B ^{[1
]}

Somorjai, RL ^{[1
]}

Orr, FW ^{[1
]}

Watson, PH ^{[1
]}

Mantsch, HH ^{[1
]}

机构：

[1] Natl Res Council Canada, Inst Biodiagnost, Winnipeg, MB R3B 1Y6, Canada

来源：

INFRARED SPECTROSCOPY: NEW TOOL IN MEDICINE, PROCEEDINGS OF | 1998年 / 3257卷

关键词：

cancer diagnosis; FTIR spectroscopy; breast cancer; tumour cells; multivariate analysis;

D O I：

10.1117/12.306098

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

Infrared spectroscopy is proving to be a powerful tool for the study and diagnosis of cancer. The application of infrared spectroscopy to the analysis of cultured tumour cells and grading of breast cancer sections is outlined. Potential sources of error in spectral interpretation due to variations in sample histology and artefacts associated with sample storage and preparation are discussed. The application of statistical techniques to assess differences between spectra and to nonsubjectively classify spectra is demonstrated.

引用

页码：24 / 34

页数：11