Treatment planning of stereotactic radiotherapy for solitary lung tumor

被引:61
作者
Takayama, K [1 ]
Nagata, Y [1 ]
Negoro, Y [1 ]
Mizowaki, T [1 ]
Sakamoto, T [1 ]
Sakamoto, M [1 ]
Aoki, T [1 ]
Yano, S [1 ]
Koga, S [1 ]
Hiraoka, M [1 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Therapeut Radiol & Oncol, Sakyo Ku, Kyoto 6068507, Japan
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2005年 / 61卷 / 05期
关键词
stereotactic radiotherapy; lung tumor; treatment planning; dose-volume histogram; normal tissue;
D O I
10.1016/j.ijrobp.2004.12.066
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Purpose: To analyze the stereotactic radiotherapy (SRT) plans in terms of internal target volume (ITV) and organs at risk (OARs). Methods and Materials: Treatment planning and dose distributions were analyzed using dose-volume histograms (DVHs) of ITV and OARs in 37 patients, who were treated for a solitary lung tumor with SRT. The stereotactic body frame (SBF) was used for immobilization and accurate setup. Prescription dose was 48 Gy four fractions at the isocenter. Results: Use of SBF limits the extent of the noncoplanar beam directions to prevent a collision with the Linac gantry. DVH analyses showed that the homogeneity index, defined as the ratio of maximum and minimum dose to ITV, ranged from 1.03 to 1.25 (mean, 1.12). The volume irradiated with 20 Gy or more (V-20) of the lung ranged from 0.3 to 11.6% (mean, 4.4%) of the whole lung volume. The maximum dose to the other OARs ranged from 0 to 11.8 Gy (mean, 0.5-2.7) per fraction. No clinically significant complications were encountered. Conclusions: Despite the limitation of the beam arrangement, a homogeneous target dose distribution, while avoiding high doses to normal tissues, was obtained. (c) 2005 Elsevier Inc.
引用
收藏
页码:1565 / 1571
页数:7
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