Outbreaks of filovirus hemorrhagic fever: Time to refocus on the patient

被引:42
作者
Bausch, Daniel G. [1 ]
Feldmann, Heinz
Geisbert, Thomas W.
Bray, Mike
Sprecher, A. G.
Boumandouki, Paul
Rollin, Pierre E.
Roth, Cathy
机构
[1] Tulane Sch Publ Hlth & Trop Med, Dept Trop Med, 1430 Tulane Ave, New Orleans, LA 70112 USA
[2] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA
[3] NIH, Bethesda, MD 20892 USA
[4] Ctr Dis Control & Prevent, Atlanta, GA USA
[5] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB, Canada
[6] Med Sans Frontieres, Brussels, Belgium
[7] Minist Hlth Populat, Brazzaville, Rep Congo
[8] WHO, CH-1211 Geneva, Switzerland
关键词
D O I
10.1086/520542
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In the 40 years since the recognition of filoviruses as agents of lethal human disease, there have been no specific advances in antiviral therapies or vaccines and few clinical studies on the efficacy of supportive care. On 20 September 2006, experts from 14 countries representing 68 institutions integrally involved in the response to outbreaks of filovirus hemorrhagic fever gathered at the National Microbiology Laboratory of the Public Health Agency of Canada in Winnipeg to discuss possible remedies for this grim situation, in a unique workshop entitled "Marburg and Ebola Hemorrhagic Fever: Feasibility of Prophylaxis and Therapy." A summary of the opportunities for and challenges to improving treatment of filovirus hemorrhagic fevers is presented here.
引用
收藏
页码:S136 / S141
页数:6
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