Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice

被引：90

作者：

Moubareck, C

Bourgeois, N

Courvalin, P

Doucet-Populaire, F

机构：

[1] Univ Paris 05, UFR Sci Pharmaceut & Biol, Microbiol Lab, Fac Sci Pharmaceut & Biol, F-75270 Paris 06, France

[2] Inst Pasteur, Unite Agents Antibacteriens, F-75724 Paris, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 09期

关键词：

D O I：

10.1128/AAC.47.9.2993-2996.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

It has been proposed that food animals represent the source of glycopeptide resistance genes present in enterococci from humans. We demonstrated the transfer of vanA and of other resistance genes from porcine to human Enterococcus faecium at high frequency in the digestive tract of gnotobiotic mice. Tylosin in the drinking water favored colonization by transconjugants.

引用

页码：2993 / 2996

页数：4

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