Liver cancer risk, coffee, and hepatitis C virus infection: a nested case-control study in Japan

被引:36
作者
Wakai, K.
Kurozawa, Y.
Shibata, A.
Fujita, Y.
Kotani, K.
Ogimoto, I.
Naito, M.
Nishio, K.
Suzuki, H.
Yoshimura, T.
Tamakoshi, A.
机构
[1] Nagoya Univ, Grad Sch Med, Dept Prevent Med Biostat & Med Decis Making, Showa Ku, Nagoya, Aichi 4668550, Japan
[2] Tottori Univ, Dept Social Med, Div Hlth Adm & Promot, Fac Med, Yonago, Tottori 6838503, Japan
[3] Kurume Univ, Sch Med, Dept Publ Hlth, Kurume, Fukuoka 8300011, Japan
[4] Niigata Univ, Grad Sch Med & Dent Sci, Dept Publ Hlth, Niigata 9518510, Japan
[5] Fukuoka Inst Hlth & Environm Sci, Dazaifu 8180135, Japan
关键词
coffee; hepatocellular carcinoma; hepatitis C virus; cohort study; nested case-control study;
D O I
10.1038/sj.bjc.6603891
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We examined hepatocellular carcinoma mortality in relation to coffee consumption and anti- hepatitis C virus ( HCV) antibody seropositivity in a nested case - control study involving 96 cases. The multivariate- adjusted odds ratios ( 95% confidence interval) for daily coffee drinkers vs non- drinkers were 0.49 ( 0.25 - 0.96), 0.31 ( 0.11 - 0.85), and 0.75 ( 0.29 - 1.92) in all cases, in HCV- positive and in HCV- negative individuals, respectively.
引用
收藏
页码:426 / 428
页数:3
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