2,2-dimethyl-4,5-diaryl-3(2H) furanone derivatives as selective cyclo-oxygenase-2 inhibitors

被引：28

作者：

Shin, SS ^{[1
]}

Noh, MS ^{[1
]}

Byun, YJ ^{[1
]}

Choi, JK ^{[1
]}

Kim, JY ^{[1
]}

Lim, KM ^{[1
]}

Ha, JY ^{[1
]}

Kim, JK ^{[1
]}

Lee, CH ^{[1
]}

Chung, S ^{[1
]}

机构：

[1] Pacific Corp, Ctr Res & Dev, Drug Discovery, Yongin Si 449900, Kyounggi Do, South Korea

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0960-894X(00)00634-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2) (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：165 / 168

页数：4

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