Phototherapy and photochemotherapy of sclerosing skin diseases

被引:29
作者
Brenner, M [1 ]
Herzinger, T [1 ]
Berking, C [1 ]
Plewig, G [1 ]
Degitz, K [1 ]
机构
[1] Univ Munich, Dept Dermatol, D-80337 Munich, Germany
关键词
photochemotherapy; phototherapy; PUVA; sclerosing skin diseases; UVA1;
D O I
10.1111/j.1600-0781.2005.00154.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
The treatment of sclerosing skin diseases [systemic sclerosis, localized scleroderma, lichen sclerosus et atrophicus, sclerodermoid graft-vs.-host disease, scleredema adultorum (Buschke), scleromyxedema and necrobiosis lipoidica] is difficult and remains a great challenge. Numerous treatments, some with potentially hazardous side effects, are currently used with only limited success. The introduction of phototherapy and photochemotherapy for sclerosing skin diseases has considerably enriched the therapeutic panel and proven useful in a number of sclerosing skin diseases especially in localized scleroderma. Two phototherapeutic modalitites are used for the treatment of sclerosing skin diseases, long-wave ultraviolet A and psoralen plus ultraviolet A (PUVA). This article reviews current knowledge about the application of phototherapy and photochemotherapy to various sclerosing skin disorders.
引用
收藏
页码:157 / 165
页数:9
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