Bismuth oxide perchlorate as a highly efficient catalyst for heteroatom acylation under solvent-free conditions

被引：81

作者：

Chakraborti, AK ^{[1
]}

Gulhane, R ^{[1
]}

Shivani ^{[1
]}

机构：

[1] NIPER, SAS Nagar 160062, Punjab, India

来源：

SYNLETT | 2003年 / 12期

关键词：

acylations; bismuth compounds; catalysis; solvent-free reactions; heteroatoms;

D O I：

10.1055/s-2003-41442

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bismuth oxide perchlorate efficiently catalyzes the acetylation of structurally diverse phenols, alcohols, thiols, and amines under solvent free conditions. Sterically hindered and electron deficient phenols are acetylated in excellent yields with stoichiometric amounts of Ac2O at room temperature. Acylation of acid-sensitive alcohols is carried out efficiently without competitive side reactions. Optically active substrates are acetylated without any detrimental effect on the optical purity.

引用

页码：1805 / 1808

页数：4

共 44 条

[1] COBALT(II) CHLORIDE CATALYZED COUPLING OF THIOLS AND ANHYDRIDES - A NEW AND EFFICIENT SYNTHESIS OF THIOL ESTERS [J].