Dietary fat is associated with metabolic syndrome in Japanese Brazilians

被引:107
作者
Freire, RD
Cardoso, MA
Gimeno, SGA
Ferreira, SRG
机构
[1] Univ Fed Sao Paulo, Dept Prevent Med, BR-04023062 Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Internal Med, Div Endocrinol, BR-04023062 Sao Paulo, Brazil
[3] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, Sao Paulo, Brazil
关键词
D O I
10.2337/diacare.28.7.1779
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - The aim of this study was to examine the association of nutrient intakes with metabolic syndrome in a Japanese descendant population at high risk for metabolic abnormalities. RESEARCH DESIGN AND METHODS - in a population-based study of Japanese Brazilians aged :30 years, 412 men and 465 women were studied. The diagnosis of metabolic syndrome was based on the National Cholesterol Education Program criteria modified for Asians. Food intake was assessed by a validated food frequency questionnaire. RESULTS - Men and women showed similar mean ages (55.7 +/- 12.7 and 54.4 +/- 11.9 years) and 49% (95% Cl 44.8-54.6) and 43% (38.4-47.6) had metabolic syndrome, respectively, As expected, clinical parameters were less favorable in the subset of subjects with metabolic syndrome. Men with metabolic syndrome showed higher cholesterol (233.2 +/- 116.3 vs. 211.7 +/- 5.8 g/day, P < 0.05) and lower carbohydrate (288.5 +/- 45.8 vs. 300.1 +/- 39.8 g/day, P < 0.001) intakes than those Without metabolic syndrome, but no difference was observed among the women. After adjusting for sex, age, smoking, education level, generation, physical activity, total energy, and dietary fiber intake, a positive association between Metabolic syndrome and total fat intake was detected. Comparing people in the highest quintile of total fat consumption with those in the lowest quintile, odds ratio (OR) of metabolic syndrome was 5.0 ([95% Cl 1.58-16.00] P < 0.005). In contrast, linoleic acid intake was inversely associated with metabolic syndrome (OR 0.50 [95% Cl 0.26-0.981 P < 0.05). Considering food groups, after adjustments only fried food intake was shown to be associated with increased risk of metabolic syndrome. CONCLUSIONS- Despite the limitation of such a study design in investigating cause-effect relationships, our findings favor the hypothesis that dietary total fat may increase whereas linoleic acid intake may reduce the risk of metabolic syndrome in Japanese descendants living in Brazil.
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页码:1779 / 1785
页数:7
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共 47 条
[1]   Prevalence of the metabolic syndrome among Omani adults [J].
Al-Lawati, JA ;
Mohammed, AJ ;
Al-Hinai, HQ ;
Jousilahti, P .
DIABETES CARE, 2003, 26 (06) :1781-1785
[2]   EFFECTS OF DIET ON CELLULAR INSULIN BINDING AND INSULIN SENSITIVITY IN YOUNG HEALTHY SUBJECTS [J].
BECKNIELSEN, H ;
PEDERSEN, O ;
SORENSEN, NS .
DIABETOLOGIA, 1978, 15 (04) :289-296
[3]   REVISION OF DIETARY ANALYSIS SOFTWARE FOR THE HEALTH HABITS AND HISTORY QUESTIONNAIRE [J].
BLOCK, G ;
COYLE, LM ;
HARTMAN, AM ;
SCOPPA, SM .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 139 (12) :1190-1196
[4]   What is an optimal diet? Relationship of macronutrient intake to obesity, glucose tolerance, lipoprotein cholesterol levels and the metabolic syndrome in the Whitehall II study [J].
Brunner, EJ ;
Wunsch, H ;
Marmot, MG .
INTERNATIONAL JOURNAL OF OBESITY, 2001, 25 (01) :45-53
[5]   Reproducibility and validity of a food frequency questionnaire among women of Japanese ancestry living in Brazil [J].
Cardoso, MA ;
Kida, AA ;
Tomita, LY ;
Stocco, PR .
NUTRITION RESEARCH, 2001, 21 (05) :725-733
[6]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497
[7]   Structure-activity relationship studies on potential non-nucleoside DABO-like inhibitors of HIV-1 reverse transcriptase [J].
Costi, R ;
Di Santo, R ;
Artico, M ;
Massa, S ;
Lavecchia, A ;
Marceddu, T ;
Sanna, L ;
La Colla, P ;
Marongiu, ME .
ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, 2000, 11 (02) :117-133
[8]   Dietary carbohydrates and insulin sensitivity: A review of the evidence and clinical implications [J].
Daly, ME ;
Vale, C ;
Walker, M ;
Alberti, KGMM ;
Mathers, JC .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1997, 66 (05) :1072-1085
[9]   Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study [J].
Djoussé, L ;
Arnett, DK ;
Pankow, JS ;
Hopkins, PN ;
Province, MA ;
Ellison, RC .
HYPERTENSION, 2005, 45 (03) :368-373
[10]   Dietary linolenic acid and carotid atherosclerosis:: the National Heart, Lung, and Blood Institute Family Heart Study [J].
Djoussé, L ;
Folsom, AR ;
Province, MA ;
Hunt, SC ;
Ellison, RC .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2003, 77 (04) :819-825