Informed lay preferences for delivery of racially varied pharmacogenomics

被引:49
作者
Bevan, JL
Lynch, JA
Dubriwny, TN
Harris, TM
Achter, PJ
Reeder, AL
Condit, CM
机构
[1] Univ Georgia, Dept Speech Commun, Athens, GA 30602 USA
[2] Univ Nevada, Greenspun Sch Commun, Las Vegas, NV 89154 USA
[3] Gainesville Coll, Gainesville, FL USA
关键词
pharmacogenomics; race; genetic discrimination; focus group methodology;
D O I
10.1097/01.GIM.0000087989.12317.3F
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Objectives: To understand public perceptions and opinions of three options for prescribing medicine: individualized genetic testing, race-based prescription, and traditional prescription. Methods: Focus groups in urban, suburban, and rural communities over-sampled for minority groups conducted from February through April, 2001 in Georgia. Results: Group members (N = 102) identified individualized genetic testing as providing the best quality of care (60% of talk turns; 75% in postdiscussion anonymous survey), but stipulated the need for protection from the invasion of privacy, discrimination, and prohibitive cost. Most individuals chose genetic testing because it provided individualized attention, and African-Americans indicated they would choose genetic testing even if the costs were high. Overall, individuals were suspicious of race-based prescription. Analyses for degree of suspicion revealed a main effect for race and an interaction effect for race and gender. Conclusions: If issues of cost, discrimination, and privacy are addressed, lay individuals prefer genetic testing as the basis for prescription of medicines that exhibit racially patterned response variation.
引用
收藏
页码:393 / 399
页数:7
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