Mitchellenes A-E, Cyclic Sesquiterpenes from the Australian Plant Eremophila mitchellii

被引：17

作者：

Barnes, Emma C. ^{[1
]}

Carroll, Anthony R. ^{[1
]}

Davis, Rohan A. ^{[1
]}

机构：

[1] Griffith Univ, Eskitis Inst, Brisbane, Qld 4111, Australia

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 09期

关键词：

ANTIMICROBIAL COMPOUNDS; ANTIBACTERIAL ACTIVITY; ARTEMISIA-ANNUA; MEDICINAL-PLANT; NATIVE PLANTS; BIOSYNTHESIS; MYOPORACEAE; IDENTIFICATION; PHYTOCHEMISTRY; CONSTITUENTS;

D O I：

10.1021/np2003676

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Chemical investigations of the Australian plant Eremophila mitchellii resulted in the isolation of the novel tetracyclic sesquiterpene lactones mitchellenes A-C (1-3), the new sesquiterpene acids mitchellenes D and E (4 and 5), and the previously reported natural products 14-hydroxy-6,12-muuroloadien-15-oic acid (6), casticin, and centaureidin. The chemical structures of all compounds were determined by extensive 1D/2D NMR and MS data analysis. Mitchellenes A-C are the first tetracyclic sesquiterpene lactones to be reported; a biosynthetic pathway is proposed for these unique secondary metabolites.

引用

页码：1888 / 1893

页数：6

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