Biochemical sensors - Adapting to nanoscale events

被引：17

作者：

Branton, D ^{[1
]}

Golovchenko, J

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

[2] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA

来源：

NATURE | 1999年 / 398卷 / 6729期

关键词：

D O I：

10.1038/19412

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ways of characterizing single-molecule events are rapidly emerging in the biochemical sciences. One such line of research now shows how measurement of ionic transport through a single, atomic-scale pore in an insulating membrane can distinguish between organic molecules of relative molecular mass as low as 100; remarkably, a single protein channel can be adapted for simultaneous analysis of a mixture of organic molecules.

引用

页码：660 / 661

页数：2

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